UFC on ESPN 38: Tsarukyan vs. Gamrot was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on June 25, 2022, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A lightweight bout between Arman Tsarukyan and former KSW Featherweight and Lightweight Champion Mateusz Gamrot headlined the event.

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